HRT is one of the most studied interventions in women's medicine — and it's also a serious medical therapy. It's not appropriate for everyone, and licensed providers carefully evaluate each candidate before prescribing.
Conditions that may rule out HRT
- Active cancer or undergoing cancer treatment
- History of blood clots (deep vein thrombosis, pulmonary embolism)
- Arterial thromboembolic disease — heart attack or stroke
- Severe liver impairment
- Undiagnosed abnormal vaginal bleeding
- Over 65 years of age
Other factors providers consider
This list is not comprehensive. Additional medical conditions, current medications, family history, and individual risk factors may affect whether HRT — and which delivery method — is appropriate for you. Eligibility is determined by a licensed provider based on a full medical evaluation.
If HRT isn't the right fit, you'll be told so during your assessment so you can pursue care that is.
Possible side effects to know about
- Breast tenderness
- Bloating
- Nausea
- Headaches
- Spotting
- Mood changes
- Skin irritation at the application site (creams)
- Changes in libido
Most side effects are mild and resolve as your body adjusts. Persistent or concerning symptoms should always be discussed with your provider.